Preparation of 2,4-diarylquinolines and substituted dihydrobenz-[c]acridines by the condensation of certain c(α),o-dilithiooximes with 2-aminobenzophenones

Author:

Park Dorothy J.,Fulmer Tammy D.,Beam Charles F.

Publisher

Wiley

Subject

Organic Chemistry

Reference6 articles.

1. A facile preparation of 4-quinolinols by the condensation of dilithiobenzoylacetone orC(α),O-dilithiooximes with methyl anthranilate or 5-chloroisatoic anhydride

2. Preparation of 2-isoxazolines from C(α),O-dilithiooximes and aldehydes and ketones

3. Neue Synthese von Chinolinderivaten

4. The electron-withdrawing ortho-substituted carbonyl group, may enhance the acidity of anilino hydrogens and cause some hydrogen abstraction by lithium diisopropylamide.

5. See: C. F. Beam, R. M. Sandifer, R. S. Foote, and C. R. Hauser, Chem. Ind., 487 (1976). We have not observed linear dehydration readily occurring under these reaction conditions, even though the resulting double bond would be in conjugation with the benzene ring.

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