1. New Local Anesthetics.1 I. Esters of 1,2-Diethyl-3-hydroxymethylpyrazolidine
2. New Local Anesthetics II: Lidocaine Analogs Embodying Pyrazolidine as the Basic Moiety
3. A related Mannich reaction between diethylhydrazine, formaldehyde and malonic acid with subsequent esterification to give 1,2-diethyl-4-ethoxycarbonylpyrazolidine has been reported by us; see ref [2].
4. Y. S. Lo and H. R. Munson, Jr., U. S. Patent 4,309,552.
5. Chem. Abstr., 96, 122790k (1982).