A new procedure for regioselective synthesis of 8,9-dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine (LY134046) and its 3-methyl analogue as inhibitors of phenylethanolamineN-methyltransferase (PNMT)-Reference-Cited by-同舟云学术

A new procedure for regioselective synthesis of 8,9-dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine (LY134046) and its 3-methyl analogue as inhibitors of phenylethanolamineN-methyltransferase (PNMT)

Published:1991-10 Issue:6 Volume:28 Page:1587-1592
ISSN:0022-152X
Container-title:Journal of Heterocyclic Chemistry
language:en
Short-container-title:

Author:

Grunewald Gary L.,Paradkar Vidyadhar M.,Stillions Duane M.,Ching Feei

Publisher

Wiley

Subject

Organic Chemistry

Reference23 articles.

1. Inhibition in vitro of rabbit adrenal norepinephrine N-methyltransferase by 2,3,4,5-tetrahydro-1H-2-benzazepines

2. 2-Benzazepines. [1,2,3]Triazolo[4,5-d][2]benzazepines and dibenzo[c,f][1,2,3]triazolo[3,4-a]azepines. Synthesis and evaluation as central nervous system agents

3. 2-Benzazepines. 5. Synthesis of pyrimido[5,4-d][2]benzazepines and their evaluation as anxiolytic agents

4. 2-Benzazepines. 6. Synthesis and pharmacological properties of the metabolites of 9-chloro-7-(2-chlorophenyl)-5H-pyrimido[5,4-d][2]benzazepine

5. L. W. Deady, N. H. Pirzada and R. D. Tposom, J. Chem. Soc., Perkin Trans. 1, 782 (1973).

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