Novel fused-ring derivatives of 2-methyl-3-o-tolyl-4(3H)quinazolone; Quinazolino [3,2-a] [1,4] benzodiazepines-Reference-Cited by-同舟云学术

Novel fused-ring derivatives of 2-methyl-3-o-tolyl-4(3H)quinazolone; Quinazolino [3,2-a] [1,4] benzodiazepines

Published:1977-11 Issue:7 Volume:14 Page:1191-1196
ISSN:0022-152X
Container-title:Journal of Heterocyclic Chemistry
language:en
Short-container-title:

Author:

Harrison D. R.,Kennewell P. D.,Taylor J. B.

Publisher

Wiley

Subject

Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jhet.5570140712/fullpdf

Reference8 articles.

1. A. H. Amin, D. R. Mekta and S. S. Samarth, “Progress in Drug Research”, E. Jucker, Ed., Vol. 14, p. 218.

2. Synthesis and central nervous system activity of quinazolones related to 2-methyl-3-(o-tolyl)-4(3H)-quinazolone (methaqualone)

3. A Combination of Methaqualone and Diphenydramine is marketed as Mandrax (R) by Roussel Laboratories, Ltd.

4. See for instance the non-equivalence of the 2-methylene protons in 3 which can only arise because of restricted rotation around the N-(2-carbomethoxyphenyl) bond.

5. N. Cohen, personal communication.

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