Author:
Bazanov Nina,Dayan Yael,Blum Jochanan,Harvey Ronald G.
Reference14 articles.
1. The Relation between Carcinogenic Activity and the Physical and Chemical Properties of Angular Benzacridines
2. Synthesis and mutagenicity of 10-azabenzo[a]pyrene-4,5-oxide and other pentacyclic aza-arene oxides.
3. Arene imine derivatives of nitrogen heterocycles: 1a,9b-dihydrobenz[h]-azirino[f]quinoline, 1a,9b-dihydrobenz[f]azirino[h]quinoline and 1a,9b-dihydroazirino[f][1,10]phenanthroline
4. Biological studies revealed that while the mutagenicity of the K-region imines derived from carbocyclic polyarenes is always substantially higher than that of the corresponding K-region oxides, the activities of the imines and oxides derived from 1,10-phenanthroline and benzo-[H]quinoline (but not of benzo[f]quinoline) [3] are of the same order of magnitude. The biological activity of the arene imines was shown to depend strongly on the position of the nitrogen atom in the skeleton of the parent heterocyclic arene. A full report on the biological tests of these compounds will be published in a separate paper.
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