Novel polycyclic heterocycles. VII. Synthesis of tetracyclic ketones and derivatives from tricyclic 5,11-dihydrodibenz[b,e][1,4] oxazepines

Author:

Petigara Ramesh B.,Yale Harry L.

Publisher

Wiley

Subject

Organic Chemistry

Reference34 articles.

1. Novel Polycyclic Heterocycles. II. Derivatives of 5,11-Dihydrodibenz[b,e][1,4]oxazepine1

2. Novel Polycyclic Heterocycles. IV.1 Structure of the Dimer of 5,11-Dihydrodibenz[b,e][1,4]oxazepine. Infrared, Proton Magnetic Resonance, and Mass Spectral Studies

3. 5,11-Dihydrodibenz[b,e][1,4]oxazepine-5-carboxamides. Compounds potentially useful in the treatment of epilepsy and trigeminal neuralgia

4. Novel polycyclic heterocycles. Derivatives of 5,11-dihydrodibenz[b,e][1,4]oxazepine and 5,11-dihydrodibenzo[b,e][1,4]thiazepine

5. In the tetracyclic ketones obtained by cyclization of phen-oxazine-, phenoselenazine-, and phenothiazine-10-propionic acids [See literature citations (8a) and (8e-h)], a single ar-substituent in the tricyclic system can lead to the formation of two isomeric products; however, the authors cited invariably assigned only one of the two possible structures, but in no instance was evidence presented to confirm these assignments. The unambiguous assignments made in this paper represent, therefore, the first application of pmr and uv spectra, and X-ray analysis, to this structural problem.

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