Lack of in vivo mutagenicity of 1,2-dichloropropane and dichloromethane in the livers of gpt delta rats administered singly or in combination

Author:

Hirata Tadashi12,Cho Young-Man1,Toyoda Takeshi1,Akagi Jun-ichi1,Suzuki Isamu13,Nishikawa Akiyoshi34,Ogawa Kumiko1

Affiliation:

1. Division of Pathology, Biological Safety Research Center; National Institute of Health Sciences; 1-18-1, Kamiyoga, Setagaya-ku Tokyo 158-8501 Japan

2. Division of Toxicology, Department of Pharmacology, Toxicology and Therapeutics, School of Pharmacy; Showa University; 1-5-8 Hatanodai, Shinagawa Tokyo 142-8555 Japan

3. Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences; Gifu University; 1-1, Yanagido Gifu 501-1193 Japan

4. National Institute of Health Science; Biological Safety Research Center; 1-18-1, Kamiyoga, Setagaya-ku Tokyo 158-8501 Japan

Publisher

Wiley

Subject

Toxicology

Reference39 articles.

1. Cytogenetic analyses of mice exposed to dichloromethane;Allen;Environ. Mol. Mutagen.,1990

2. Carcinogenicity of perfluorooctanoic acid, tetrafluoroethylene, dichloromethane, 1,2-dichloropropane, and 1,3-propane sultone;Benbrahim-Tallaa;Lancet Oncol.,2014

3. Oral toxicity of 1,2-dichloropropane: acute, short-term, and long-term studies in rats;Bruckner;Fundam. Appl. Toxicol.,1989

4. Mutagenicity of pesticides containing 1,3-dichloropropene;De Lorenzo;Cancer Res.,1977

5. 1,2-Dichloropropane hepatotoxicity in rats after inhalation exposure;Di Nucci;J. Appl. Toxicol.,1990

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