Recent advancements in biomedical application of polylactic acid/graphene nanocomposites: An overview

Author:

Adekoya Gbolahan Joseph1,Ezika Anthony Chidi1,Adekoya Oluwasegun Chijioke1,Sadiku Emmanuel Rotimi1,Hamam Yskandar23,Ray Suprakas Sinha45ORCID

Affiliation:

1. Institute of NanoEngineering Research (INER) Department of Chemical, Metallurgical and Materials Engineering Faculty of Engineering and the Built Environment Tshwane University of Technology Pretoria South Africa

2. French South African Institute of Technology (F’SATI)/Department of Electrical Engineering Tshwane University of Technology Pretoria South Africa

3. École Supérieure d’Ingénieurs en Électrotechnique et Électronique Paris France

4. Centre for Nanostructures and Advanced Materials DSI‐CSIR Nanotechnology Innovation Centre Council for Scientific and Industrial Research CSIR Pretoria South Africa

5. Department of Chemical Sciences University of Johannesburg Johannesburg South Africa

Abstract

AbstractPolylactic acid (PLA)‐graphene nanocomposites have attracted significant attention in the biomedical field because of their biodegradability, biocompatibility, and excellent mechanical properties. This review provides a comprehensive summary of the recent developments in the biomedical applications of PLA/graphene nanocomposites. The discussed applications include tissue engineering, drug delivery, biomedical imaging and sensing, antimicrobial and anticancer treatments, and photothermal and photodynamic therapies. The properties and synthesis of these nanocomposites are also addressed. This review shows that although significant advancements have been made in the development of biomedical applications for PLA/graphene nanocomposites, further research is still required to overcome the existing challenges and limitations, such as improving biocompatibility and biodegradability and optimizing synthesis and processing methods. Despite these challenges, the potential of PLA/graphene nanocomposites in the biomedical field is significant and holds promise for future advancements.

Funder

Department of Science and Innovation, South Africa

National Research Foundation

Publisher

Wiley

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