Carbon‐based nanodots for biomedical applications and clinical transformation prospects

Author:

Ding Haizhen12,Xiao Tenghui12,Ren Fangfang12,Qiu Yu12,Shen Zhiyang12,Chen Xuecheng3,Mijowska Ewa3,Chen Hongmin12ORCID

Affiliation:

1. State Key Laboratory of Vaccines for Infectious Diseases Center for Molecular Imaging and Translational Medicine Xiang an Biomedicine Laboratory School of Public Health Xiamen University Xiamen China

2. State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics National Innovation Platform for Industry‐Education Integration in Vaccine Research Xiamen University Xiamen China

3. Faculty of Chemical Technology and Engineering West Pomeranian University of Technology Szczecin Poland

Abstract

AbstractCarbon dots (CDs), emerging as a promising class of nanomaterials, have garnered significant interest in the field of biomedicine due to their unique physicochemical properties. This review provides a comprehensive overview of the recent advancements in the biomedical applications of CDs, emphasizing their potential for revolutionizing diagnostics, therapy, and bio‐imaging. We discuss the synthesis and functionalization of CDs, which are pivotal in tailoring their properties for specific biomedical applications. The applications of CDs in bioimaging include fluorescence imaging, magnetic resonance imaging, photoacoustic imaging, etc. Additionally, this review delves into the benefits of CDs in the treatment of diseases including cancer, inflammation and Alzheimer's, etc. Finally, we look forward to the future of CDs in the field of biomedicine, emphasizing the necessity of interdisciplinary collaboration to overcome current obstacles and facilitate the clinical translation of CDs‐based technologies. This review aims to provide a summary and perspectives on the latest developments of CDs in biomedicine, hoping to inspire further research in this rapidly advancing field.

Funder

National Natural Science Foundation of China

Science Fund for Distinguished Young Scholars of Fujian Province

Publisher

Wiley

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