Application of proteometric approach for identification of functional mutant sites to improve the binding affinity of anticancer biologic trastuzumab with its antigen human epidermal growth factor receptor 2-Reference-Cited by-同舟云学术

Application of proteometric approach for identification of functional mutant sites to improve the binding affinity of anticancer biologic trastuzumab with its antigen human epidermal growth factor receptor 2

Published:2019-11-06 Issue:2 Volume:33 Page:
ISSN:0952-3499
Container-title:Journal of Molecular Recognition
language:en
Short-container-title:J Mol Recognit

Author:

Balakrishnan Nataraj¹^ORCID,Gurunathan Baskar²^ORCID,Surapaneni Krishna Mohan³^ORCID

Affiliation:

1. Biotechnology Division, R&D CentreOrchid Pharma Ltd. (Formerly known as Orchid Chemicals and Pharmaceuticals Ltd.) Chennai India

2. Department of BiotechnologySt. Joseph's College of Engineering Chennai India

3. Department of BiochemistryPanimalar Medical College Hospital & Research Institute Chennai India

Publisher

Wiley

Subject

Molecular Biology,Structural Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jmr.2818

Reference25 articles.

1. p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor.

2. Humanization of an anti-p185HER2 antibody for human cancer therapy.

3. SliwkowskiM.Humanized anti‐ErbB2 antibodies and treatment with anti‐ErbB2 antibodies.2005.

4. The Evolution of Biosimilars in Oncology, with a Focus on Trastuzumab

5. Essential medicines for breast cancer in low and middle income countries

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