Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness-Reference-Cited by-同舟云学术

Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness

Published:2015-12-11 Issue:2 Volume:171 Page:276-289
ISSN:1552-4841
Container-title:American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
language:en
Short-container-title:Am. J. Med. Genet.

Author:

Bigdeli Tim B.¹,Ripke Stephan²³,Bacanu Silviu-Alin¹,Lee Sang Hong⁴,Wray Naomi R.⁴,Gejman Pablo V.⁵⁶,Rietschel Marcella⁷,Cichon Sven⁸⁹¹⁰¹¹,St Clair David¹²,Corvin Aiden¹³,Kirov George¹⁴,McQuillin Andrew¹⁵,Gurling Hugh¹⁵,Rujescu Dan¹⁶¹⁷,Andreassen Ole A.¹⁸¹⁹,Werge Thomas²⁰²¹²²,Blackwood Douglas H. R.²³,Pato Carlos N.²⁴²⁵,Pato Michele T.²⁴²⁵,Malhotra Anil K.²⁶²⁷²⁸,O'Donovan Michael C.¹⁴²⁹,Kendler Kenneth S.¹³⁰,Fanous Ayman H.¹²⁴³¹³²,

Affiliation:

1. Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry; Virginia Commonwealth University; Richmond Virginia

2. Analytic and Translational Genetics Unit; Massachusetts General Hospital; Boston Massachusetts

3. Stanley Center for Psychiatric Research; Broad Institute of MIT and Harvard; Cambridge Massachusetts

4. Queensland Brain Institute, The University of Queensland; Brisbane Queensland Australia

5. Department of Psychiatry and Behavioral Sciences; NorthShore University HealthSystem; Evanston Illinois

6. Department of Psychiatry and Behavioral Neuroscience; University of Chicago; Chicago Illinois

7. Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim; University of Heidelberg; Heidelberg Germany

8. Division of Medical Genetics, Department of Biomedicine; University of Basel; Basel Switzerland

9. Institute of Human Genetics; University of Bonn; Bonn Germany

10. Department of Genomics; Life and Brain Center; Bonn Germany

11. Institute of Neuroscience and Medicine (INM-1); Research Center Juelich; Juelich Germany

12. University of Aberdeen, Institute of Medical Sciences; Aberdeen Scotland United Kingdom

13. Neuropsychiatric Genetics Research Group; Department of Psychiatry; Trinity College Dublin; Ireland

14. MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine; Cardiff University; Cardiff United Kingdom

15. Molecular Psychiatry Laboratory, Division of Psychiatry; University College London; United Kingdom

16. Department of Psychiatry; University of Halle; Halle Germany

17. Department of Psychiatry; University of Munich; Munich Germany

18. NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine; University of Oslo; Oslo Norway

19. Division of Mental Health and Addiction; Oslo University Hospital; Oslo Norway

20. Institute of Biological Psychiatry, MHC Sct. Hans; Mental Health Services Copenhagen; Denmark

21. Department of Clinical Medicine; University of Copenhagen; Copenhagen Denmark

22. The Lundbeck Foundation Initiative for Integrative Psychiatric Research; iPSYCH; Denmark

23. Division of Psychiatry; University of Edinburgh; Edinburgh United Kingdom

24. Department of Psychiatry; Keck School of Medicine at University of Southern California; Los Angeles California

25. Zilkha Neurogenetics Institute; Keck School of Medicine at University of Southern California; Los Angeles California

26. The Zucker Hillside Hospital; Glen Oaks New York

27. The Feinstein Institute for Medical Research; Manhasset New York

28. The Hofstra NS-LIJ School of Medicine; Hempstead New York

29. National Centre for Mental Health; Cardiff University; Cardiff Wales

30. Department of Human and Molecular Genetics; Virginia Commonwealth University School of Medicine; Richmond Virginia

31. Mental Health Service Line; Washington VA Medical Center; Washington District of Columbia

32. Department of Psychiatry; Georgetown University School of Medicine; Washington District of Columbia

Funder

United States Department of Veterans Affairs Merit Review Program

Netherlands Scientific Organization

Dutch Brain Foundation and the VU University Amsterdam

Seventh Framework Programme

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Psychiatry and Mental health,Genetics(clinical)

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5. The correlation between relatives on the supposition of Mendelian inheritance;Fisher;Philos Trans R Soc Edinb,1918

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