Evidence for additionally increased apoptosis in the peripheral blood mononuclear cells of major depressive patients with a high risk for suicide

Author:

Amidfar Meysam12ORCID,Kim Yong-Ku3,Scaini Giselli4,Quevedo João4567

Affiliation:

1. Fasa University of Medical Sciences; Fasa Iran

2. Department of Neuroscience, School of Advanced Technologies in Medicine; Tehran University of Medical Sciences; Tehran Iran

3. Department of Psychiatry; College of Medicine, Ansan Hospital, Korea University; Seoul Republic of Korea

4. Translational Psychiatry Program, Department of Psychiatry and Behavioral Sciences, McGovern Medical School; The University of Texas Health Science Center at Houston (UTHealth); Houston Texas

5. Laboratory of Neurosciences, Graduate Program in Health Sciences, Health Sciences Unit; University of Southern Santa Catarina (UNESC); Criciuma Santa Catarina Brazil

6. Department of Psychiatry and Behavioral Sciences, Center of Excellence on Mood Disorders, McGovern Medical School; The University of Texas Health Science Center at Houston (UTHealth); Houston Texas

7. Neuroscience Graduate Program; The University of Texas Graduate School of Biomedical Sciences at Houston; Houston Texas

Funder

Health Ministry of Iran

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Psychiatry and Mental health,Genetics (clinical)

Reference57 articles.

1. Increased apoptosis of T cell subsets in aging humans: Altered expression of Fas (CD95), Fas ligand, Bcl-2, and Bax;Aggarwal;Journal of Immunology,1998

2. A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality;Bay-Richter;Brain, Behavior, and Immunity,2015

3. Affective disorders and suicide risk: A reexamination;Bostwick;Am J Psychiatry,2000

4. Fluoxetine up-regulates expression of cellular FLICE-inhibitory protein and inhibits LPS-induced apoptosis in hippocampus-derived neural stem cell;Chiou;Biochemical and Biophysical Research Communications,2006

5. Moclobemide upregulated Bcl-2 expression and induced neural stem cell differentiation into serotoninergic neuron via extracellular-regulated kinase pathway;Chiou;British Journal of Pharmacology,2006

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