Association and ancestry analysis of sequence variants in ADH and ALDH using alcohol-related phenotypes in a Native American community sample

Author:

Peng Qian12,Gizer Ian R.3,Libiger Ondrej2,Bizon Chris4,Wilhelmsen Kirk C.45,Schork Nicholas J.1,Ehlers Cindy L.6

Affiliation:

1. Department of Human Biology; J. Craig Venter Institute; La Jolla California

2. Scripps Translational Science Institute; The Scripps Research Institute; La Jolla California

3. Department of Psychological Sciences; University of Missouri-Columbia; Columbia Missouri

4. Renaissance Computing Institute; University of North Carolina at Chapel Hill; Chapel Hill North Carolina

5. Department of Genetics and Neurology; University of North Carolina at Chapel Hill; Chapel Hill North Carolina

6. Department of Molecular and Cellular Neuroscience; The Scripps Research Institute; La Jolla California

Funder

National Institutes of Health

National Institute on Alcoholism and Alcohol Abuse

National Center on Minority Health and Health Disparities

National Institute of Drug Abuse

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Psychiatry and Mental health,Genetics(clinical)

Reference50 articles.

1. An integrated map of genetic variation from 1,092 human genomes;Abecasis;Nature,2012

2. Fast model-based estimation of ancestry in unrelated individuals;Alexander;Genome Res,2009

3. Controlling the false discovery rate: A practical and powerful approach to multiple testing;Benjamini;J R Statis Soc B,1995

4. Variant calling in low-coverage whole genome sequencing of a Native American population sample;Bizon;BMC Genomics,2014

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