MiR-506 suppresses proliferation and induces senescence by directly targeting the CDK4/6-FOXM1 axis in ovarian cancer

Author:

Liu Guoyan12,Sun Yan13,Ji Ping1,Li Xia14,Cogdell David1,Yang Da1,Parker Kerrigan Brittany C1,Shmulevich Ilya5,Chen Kexin36,Sood Anil K789,Xue Fengxia2,Zhang Wei19

Affiliation:

1. Department of Pathology; University of Texas MD Anderson Cancer Center; Houston TX USA

2. Department of Gynecology and Obstetrics; Tianjin Medical University General Hospital; People's Republic of China

3. Department of Pathology; Tianjin Medical University Cancer Institute and Hospital; People's Republic of China

4. Department of Biochemistry and Molecular Biology, State Key Laboratory of Cancer Biology; Fourth Military Medical University; Xi'an People's Republic of China

5. Institute for Systems Biology; Seattle WA USA

6. Department of Epidemiology and Biostatistics; Tianjin Medical University Cancer Institute and Hospital; People's Republic of China

7. Department of Gynecologic Oncology and Reproductive Medicine; University of Texas MD Anderson Cancer Center; Houston TX USA

8. Department of Cancer Biology; University of Texas MD Anderson Cancer Center; Houston TX USA

9. Center for RNAi and Non-Coding RNA; University of Texas MD Anderson Cancer Center; Houston TX USA

Funder

National Institutes of Health

National Key Scientific and Technological Project

Tianjin Science and Technology Committee Foundation

Publisher

Wiley

Subject

Pathology and Forensic Medicine

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