Development of a precise quantitative method for monitoring sirolimus in whole blood using LC/ESI

Development of a precise quantitative method for monitoring sirolimus in whole blood using LC/ESI–MS/MS

Published:2020-05-22 Issue:8 Volume:34 Page:
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Shigeta Kensuke¹,Kikuchi Masafumi¹²,Tanaka Masaki²,Takasaki Shinya²,Oishi Hisashi³,Sado Tetsu³,Matsuda Yasushi³,Noda Masafumi³,Okada Yoshinori³,Mano Nariyasu¹²^ORCID,Yamaguchi Hiroaki¹²⁴^ORCID

Affiliation:

1. Faculty of Pharmaceutical SciencesTohoku University Sendai Japan

2. Department of Pharmaceutical sciencesTohoku University Hospital Sendai Japan

3. Department of Thoracic SurgeryTohoku University Hospital Sendai Japan

4. Yamagata University Graduate School of Medicine/Department of PharmacyYamagata University Hospital Yamagata Japan

Funder

Japan Research Foundation for Clinical Pharmacology

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.4853

Reference26 articles.

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2. The addition of sirolimus to the graft-versus-host disease prophylaxis regimen in reduced intensity allogeneic stem cell transplantation for lymphoma: a multicentre randomized trial

3. Lung function response and side effects to rapamycin for lymphangioleiomyomatosis: a prospective national cohort study

4. 13C labelled internal standards—A solution to minimize ion suppression effects in liquid chromatography–tandem mass spectrometry analyses of drugs in biological samples?

5. Falsely high sirolimus concentrations due to everolimus cross-reactivity in the Siemens sirolimus immunoassay: Corrective actions implemented

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