Randomized codon mutagenesis reveals that the HIV Rev arginine-rich motif is robust to substitutions and that double substitution of two critical residues alters specificity-Reference-Cited by-同舟云学术

Randomized codon mutagenesis reveals that the HIV Rev arginine-rich motif is robust to substitutions and that double substitution of two critical residues alters specificity

Published:2013-04-18 Issue:6 Volume:26 Page:286-296
ISSN:0952-3499
Container-title:Journal of Molecular Recognition
language:en
Short-container-title:J. Mol. Recognit.

Author:

Possik Elite J.¹,Bou Sleiman Maroun S.²,Ghattas Ingrid R.³,Smith Colin A.³

Affiliation:

1. McGill Cancer Centre and Department of Biochemistry; McGill University; Montreal; Quebec; Canada

2. Doctoral Program in Molecular Life Sciences; Ecole Polytechnique Fédérale de Lausanne; Lausanne; Switzerland

3. Department of Biology; American University of Beirut; Beirut; Lebanon

Publisher

Wiley

Subject

Molecular Biology,Structural Biology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jmr.2272/fullpdf

Reference56 articles.

1. HIV-1 Rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA;Bartel;Cell,1991

2. α helix-RNA major groove recognition in an HIV-1 rev peptide-RRE RNA complex;Battiste;Science,1996

3. Binding of an HIV Rev peptide to Rev responsive element RNA induces formation of purine-purine base pairs;Battiste;Biochemistry,1994

4. Arginine-rich motifs present multiple interfaces for specific binding by RNA;Bayer;RNA,2005

5. Thermodynamic prediction of protein neutrality;Bloom;Proc. Natl. Acad. Sci. U. S. A.,2005

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Aptamers in Virology—A Consolidated Review of the Most Recent Advancements in Diagnosis and Therapy;Pharmaceutics;2021-10-09

2. Sequence and Functional Variation in the HIV-1 Rev Regulatory Axis;Current HIV Research;2020-03-25

3. Altered‐specificity mutants of the HIV Rev arginine‐rich motif‐RRE IIB interaction;Journal of Molecular Recognition;2020-01-10

4. HK022 Nun Requires Arginine-Rich Motif Residues Distinct from λ N;Journal of Bacteriology;2015-11-15

5. Functional Advantages of Conserved Intrinsic Disorder in RNA-Binding Proteins;PLOS ONE;2015-10-06