Limb–body wall complex: Literature review and case report

Author:

Cortés‐Enríquez Omar Daniel1ORCID,Tapia‐Fonseca Claudia Vanessa1,Torres‐Fuentes María Angelina1,Torres‐Riojas Paola Berenice1,Raya‐Garza Laura Patricia1

Affiliation:

1. Hospital General de Zona con Medicina Familiar No. 6. Instituto Mexicano del Seguro Social San Nicolas de los Garza Mexico

Abstract

AbstractIntroductionBody wall anomalies comprise a wide range of malformations. Limb–Body wall complex (LBWC) represents the most severe presentation of this group, with life threatening malformations in practically all the cases, including craniofacial, body wall defects, and limb anomalies. There is no consensus about its etiology and folding and gastrulation defects have been involved. Also, impaired angiogenesis has been proposed as a causative process.Case ReportWe present the case of a masculine stillborn, product of the first pregnancy in a 15‐year‐old, apparently healthy mother. He was delivered at 31 weeks of gestation due to an early rupture of membranes. He presented with multiple malformations including a wide body wall defect with multiple organ herniation and meromelia of the lower right limb.Discussion and ConclusionsLBWC represents a severe and invariably fatal pathology. There are no described risk factors, nevertheless, this case presented in a teenage mother, a well‐described risk factor for other body wall anomalies. Its diagnosis allows us to discriminate between other pathologies that require prenatal or postnatal specialized treatment.

Publisher

Wiley

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