Outcomes of Supracricoid Partial Laryngectomy Performed in the United States: A Systematic Review

Author:

Saturno Michael12ORCID,Shaari Ariana L.12ORCID,Yun Jun12,Wein Lauren E.12,Shaari Diana1,Kappauf Catharine2,Laitman Benjamin M.2ORCID,Chai Raymond L.2

Affiliation:

1. Thyroid, Head, and Neck Cancer (THANC) Foundation New York New York U.S.A.

2. Department of Otolaryngology – Head and Neck Surgery Icahn School of Medicine at Mount Sinai New York New York U.S.A.

Abstract

ObjectiveThe primary objective of this study was to evaluate oncologic outcomes of all published cases of supracricoid partial laryngectomy (SCPL) performed in the United States. The secondary objective was to assess the functional outcomes associated with this procedure.Review MethodsA systematic review of PubMed, SCOPUS, and Embase for all English‐language studies pertaining to SCPL performed in the United States was conducted until August 2021. Primary outcomes included disease‐specific survival (DSS), overall survival, and local recurrence rate. Secondary outcomes included larynx preservation rate, gastrostromy tube dependency, days to gastrostomy tube removal, decannulation rate, and days to decannulation.ResultsA total of six studies were included in the analysis. A total of 113 patients (58.5%) underwent SCPL surgery as a primary treatment method whereas 80 patients (41.5%) underwent SCPL as salvage surgery. The 5‐year DSS rates were 87.8% and 100% for primary and salvage procedures, respectively. Approximately 10.3% of patients undergoing a salvage SCPL procedure experienced a local recurrence whereas only 1.85% of primary SCPL procedures resulted in local recurrence. The rates of decannulation following primary and salvage SCPL were 92.7% and 88.1%, respectively. With regard to swallowing, primary and salvage SCPL procedures demonstrated comparably low postoperative gastrostomy tube dependency rates of 3.66% and 4.76%, respectively.ConclusionsSCPL performed in the United States is an effective surgical technique that produces excellent outcomes in qualifying patients, thus validating its viability as an organ‐preserving surgical alternative. Laryngoscope, 2024

Publisher

Wiley

Subject

Otorhinolaryngology

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