Study on preparation of pregna‐4‐en‐17<i>α</i>,21‐diol‐3,20‐dione from androst‐4‐en‐3,17‐dione-Reference-Cited by-同舟云学术

Study on preparation of pregna‐4‐en‐17α,21‐diol‐3,20‐dione from androst‐4‐en‐3,17‐dione

Published:2021-12 Issue:6 Volume:59 Page:830-835
ISSN:2572-8288
Container-title:Vietnam Journal of Chemistry
language:en
Short-container-title:Vietnam Journal of Chemistry

Author:

Huy Luu Duc¹,Tu Duong N.¹,Diep Nguyen T.¹,Khanh Ho V.¹,Kazantsev A. V.²,Savinova T. S.³

Affiliation:

1. Institute of Chemistry, Vietnam Academy of Science and Technology 18 Hoang Quoc Viet, Cau Giay Hanoi 10000 Viet Nam

2. M. V. Lomonosov Moscow State University, Faculty of Chemistry Build. 3, 1 Lenin Hills, 119991 Moscow Russia

3. F. F. Erisman Federal Scientific Center of Hygiene of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing Russian Federation building 2, Semashko street Mytishchi, Moscow region Russian Federation 141014

Abstract

AbstractAn efficient procedure was proposed for the preparation of pregna‐4‐en‐17α,21‐diol‐3,20‐dioneby using nitrile method to result in high yield up to 56.0‐57.0 % from androst‐4‐en‐3,20‐dione, a key intermediate for producing corticoids.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/vjch.202100052

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