Electrochemical determination of salbutamol in aqueous solutions with UiO‐66/rGO‐modified electrodes

Author:

Thanh Nhi Le Thi12,Hoa Le Thi3,Uyen Dam To4,Sinh Le Hoang5,Nguyen Do Mai3,Bach Ta Ngoc6,Tam Toan Tran Thanh7,Quang Khieu Dinh3

Affiliation:

1. Center for Advanced Chemistry Institute of Research and Development Duy Tan University Da Nang Vietnam

2. Faculty of Natural Sciences Duy Tan University Da Nang Vietnam

3. Department of Chemistry University of Sciences Hue University Hue Vietnam

4. Department of Pharmacy Nguyen Tat Thanh University Ho Chi Minh City Vietnam

5. VN‐UK Institute for Research and Executive Education University of Danang Da Nang Vietnam

6. Institute of Materials Science Vietnam Academy of Science and Technology Hanoi Vietnam

7. Dong A University Da nang Vietnam

Abstract

AbstractThe synthesis of the UiO‐66/rGO material involved combining UiO‐66 with reduced graphene oxide (rGO). This resulting composite found application in the electrochemical determination of salbutamol (SAL) through modification of a glassy‐carbon electrode (GCE) with UiO‐66/rGO. Differential pulse voltammetry served as the chosen technique, offering a wide linear range spanning 1–160 µm and demonstrating a low limit of detection at 0.84 µm. To ensure the reliability of the electrode, various aspects such as sensitivity, repeatability, reproducibility, and stability were meticulously studied. When applied to the analysis of SAL in swine urine solutions (n = 3), the electrode exhibited good recovery rates. Remarkably, the results obtained through this method correlated well with those acquired using ultra‐high performance liquid chromatography (UPLC).

Publisher

Wiley

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