GAP promoter-based fed-batch production of highly bioactive core streptavidin byPichia pastoris

Author:

Müller Jakob Michael1,Bruhn Simon1,Flaschel Erwin1,Friehs Karl1,Risse Joe Max1

Affiliation:

1. Lehrstuhl Für Fermentationstechnik, Technische Fakultät, Universität Bielefeld; PF 10 01 31 Bielefeld D-33501 Germany

Publisher

Wiley

Subject

Biotechnology

Reference65 articles.

1. The properties of streptavidin, a biotin-binding protein produced by streptomycetes;Chaiet;Arch Biochem Biophys.,1964

2. Antibiotic MSD-235. I. Production by Streptomyces avidinii and Streptomyces lavendulae;Stapley;Antimicrob Agents Chemother (Bethesda).,1963

3. Application of avidin-biotin technology to affinity-based separations;Bayer;J Chromatogr A.,1990

4. Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH;Katz;J Mol Biol.,1997

5. Extremely high thermal stability of streptavidin and avidin upon biotin binding;González;Biomol Eng.,1999

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