Alpha‐globin gene triplication and its effect in beta‐thalassemia carrier, sickle cell trait, and healthy individual

Author:

Hamid Mohammad1ORCID,keikhaei Bijan2,Galehdari Hamid3,Saberi Alihossein4,Sedaghat Alireza5,Shariati Gholamreza46,Mohammadi‐Anaei Marziye6

Affiliation:

1. Department of Molecular Medicine, Biotechnology Research Center Pasteur Institute of Iran Tehran Iran

2. Research Center for Thalassemia and Hemoglobinopathy, Health Institute Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran

3. Department of Genetics, Faculty of Sciences Shahid Chamran University of Ahvaz Ahvaz Iran

4. Department of Medical Genetics, Faculty of Medicine Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran

5. Department of Endocrinology Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran

6. Narges Medical Genetics and PND Laboratory Ahvaz Iran

Publisher

Wiley

Reference36 articles.

1. The Thalassaemia Syndromes

2. TaherA VichinskyE MusallamK CappelliniMD ViprakasitV.Guidelines for the management of non transfusion dependent thalassaemia (NTDT). Nicosia Cyprus: Thalassaemia International Federation;2013.

3. Different hematological phenotypes caused by the interaction of triplicated α-globin genes and heterozygous β-thalassemia

4. Betathalassaemia heterozygotes with alpha‐globin gene triplication;Colah RB;Br J Haematol,1997

5. Beta‐thalassaemia intermedia: is it possible consistently to predict phenotype from genotype?

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