Population PKPD of voclosporin in renal allograft patients

Author:

Mayo P.R.1,Ling S.Y.1,Huizinga R.B.1,Freitag D.G.1,Aspeslet L.J.1,Foster R.T.1

Affiliation:

1. Isotechnika Pharma Inc.; Edmonton AB Canada

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference22 articles.

1. Immunosuppression: evolution in practice and trends, 1994-2004;Meier-Kriesche;Am J Transpl.,2006

2. Sirolimus in combination with tacrolimus is associated with worse renal allograft survival compared to mycophenolate mofetil combined with tacrolimus;Meier-Kriesche;Am J Transpl.,2005

3. Tacrolimus versus cyclosporin as primary immunosuppression for kidney transplant recipients;Webster;Cochrane Database Syst Rev.,2005

4. Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin);Kuglstatter;Acta Crystallogr D Biol Crystallogr.,2011

5. Calcineurin phosphatase activity in T lymphocytes is inhibited by FK506 and cyclosporin A;Fruman;Proc Natl Acad Sci USA,1992

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