In Situ Tumor Vaccination with Calcium‐Linked Degradable Coacervate Nanocomplex Co‐Delivering Photosensitizer and TLR7/8 Agonist to Trigger Effective Anti‐Tumor Immune Responses

Author:

Liu Yutong1,Li Hui1,Zhao Huajun2,Hao Yanyun1,Van Herck Simon3,Xu Zejun4,Wang Guan5,Wang Xiao6,Zhang Xinke7,Ge Xiaoyan1,Li Xia1,Yang Ailu2,Chen Hongfei1,Zou Jing1,Wang Wentao8,De Geest Bruno G.3,Zhang Zhiyue1ORCID

Affiliation:

1. Department of Pharmaceutics Key Laboratory of Chemical Biology (Ministry of Education) School of Pharmaceutical Sciences Cheeloo College of Medicine Shandong University Jinan 250012 P. R. China

2. Institute of Immunopharmaceutical Sciences School of Pharmaceutical Sciences Shandong University Jinan 250012 P. R. China

3. Department of Pharmaceutics Ghent University Ottergemsesteenweg 460 Ghent 9000 Belgium

4. Department of Natural Products Chemistry Key Laboratory of Chemical Biology (Ministry of Education) School of Pharmaceutical Sciences Shandong University 44 Wenhuaxi Road Jinan 250012 P. R. China

5. Department of Immunology College of Basic Medical Science Dalian Medical University Dalian 116044 P. R. China

6. School of Pharmaceutical Sciences Cheeloo College of Medicine Shandong University 44 Wenhuaxi Road Jinan 250012 P. R. China

7. Key Laboratory of Chemical Biology (Ministry of Education) NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate‐based Medicine Department of Pharmacology School of Pharmaceutical Sciences Cheeloo College of Medicine Shandong University 44 Wenhuaxi Road Jinan 250012 P. R. China

8. Department of General Surgery Shandong Qianfoshan Hospital Cheeloo College of Medicine Shandong University Jinan 250014 P. R. China

Funder

Natural Science Foundation of Shandong Province

National Natural Science Foundation of China

Publisher

Wiley

Subject

Pharmaceutical Science,Biomedical Engineering,Biomaterials

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