1. Laboratory of DDS Design and Drug Disposition Graduate School of Pharmaceutical Sciences Chiba University 1‐8‐1, Inohana, Chuo‐ku, Chiba Chiba 260‐0856 Japan
2. Laboratory of DDS Design and Drug Disposition Graduate School of Pharmaceutical Sciences Tohoku University 6‐3, Aoba, Aramaki, Aoba‐ku Sendai Miyagi 980‐8578 Japan
3. Laboratory of Organic Chemistry for Drug Development Faculty of Pharmaceutical Sciences Hokkaido University Kita 12, Nishi 6, Kita‐ku Sapporo Hokkaido 060‐0812 Japan
4. DDS Research Laboratory NOF CORPORATION 3‐3, Chidoricho, Kawasaki‐ku Kawasaki Kanagawa 210‐0865 Japan