Affiliation:
1. Department of Electrical and Computer Engineering University of Pittsburgh Pittsburgh PA 15261 USA
2. Department of Mechanical Engineering and Materials Science University of Pittsburgh Pittsburgh PA 15261 USA
3. Department of BioEngineering University of Pittsburgh Pittsburgh PA 15261 USA
4. Department of Anesthesiology and Perioperative University of Pittsburgh Pittsburgh PA 15261 USA
Abstract
AbstractContinuous, noninvasive blood pressure (CNIBP) monitoring provides valuable hemodynamic information that renders detection of the early onset of cardiovascular diseases. Wearable mechano‐electric pressure sensors that mount on the skin are promising candidates for monitoring continuous blood pressure (BP) pulse waveforms due to their excellent conformability, simple sensing mechanisms, and convenient signal acquisition. However, it is challenging to acquire high‐fidelity BP pulse waveforms since it requires highly sensitive sensors (sensitivity larger than 4 × 10−5 kPa−1) that respond linearly with pressure change over a large dynamic range, covering the typical BP range (5–25 kPa). Herein, this work introduces a high‐fidelity, iontronic‐based tonometric sensor (ITS) with high sensitivity (4.82 kPa−1), good linearity (R2 > 0.995), and a large dynamic range (up to 180% output change) over a broad working range (0 to 38 kPa). Additionally, the ITS demonstrates a low limit of detection at 40 Pa, a fast load response time (35 ms) and release time (35 ms), as well as a stable response over 5000 load per release cycles, paving ways for potential applications in human‐interface interaction, electronic skins, and robotic haptics. This work further explores the application of the ITS in monitoring real‐time, beat‐to‐beat BP by measuring the brachial and radial pulse waveforms. This work provides a rational design of a wearable pressure sensor with high sensitivity, good linearity, and a large dynamic range for real‐time CNIBP monitoring.
Subject
Pharmaceutical Science,Biomedical Engineering,Biomaterials
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献