Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1-Reference-Cited by-同舟云学术

Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1

Published:2015-10-09 Issue:1 Volume:63 Page:49-62
ISSN:0270-9139
Container-title:Hepatology
language:en
Short-container-title:Hepatology

Author:

Perin Paula M.¹,Haid Sibylle¹,Brown Richard J.P.¹,Doerrbecker Juliane¹,Schulze Kai²,Zeilinger Carsten³,von Schaewen Markus⁴,Heller Brigitte⁴,Vercauteren Koen⁵,Luxenburger Eva⁶,Baktash Yasmine M.⁷,Vondran Florian W.R.⁸⁹,Speerstra Sietkse¹⁰¹¹,Awadh Abdullah¹¹¹²,Mukhtarov Furkat¹⁰¹¹,Schang Luis M.¹⁰¹¹¹²,Kirschning Andreas³,Müller Rolf⁶,Guzman Carlos A.²,Kaderali Lars¹³,Randall Glenn⁷,Meuleman Philip⁵,Ploss Alexander⁴,Pietschmann Thomas¹⁹

Affiliation:

1. Institute of Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover and the Helmholtz Centre for Infection Research; Hannover Germany

2. Department of Vaccinology and Applied Microbiology; Helmholtz Centre of Infection Research; Braunschweig Germany

3. Institute of Organic Chemistry and Center of Biomolecular Drug Research, Leibniz Universität; Hannover Germany

4. Department of Molecular Biology; Princeton University; Princeton NJ

5. Center for Vaccinology; Ghent University; Ghent Belgium

6. Helmholtz Institute for Pharmaceutical Research Saarland; Saarbrücken Germany

7. Department of Microbiology; The University of Chicago; Chicago IL

8. ReMediES, Department of General; Visceral and Transplantation Surgery, Hannover Medical School; Hannover Germany

9. German Centre for Infection Research, Hannover-Braunschweig; Germany

10. Department of Biochemistry; University of Alberta; Edmonton AB Canada

11. Li Ka Shing Institute of Virology, University of Alberta; Edmonton AB Canada

12. Department of Medical Microbiology and Immunology; University of Alberta; Edmonton AB Canada

13. Technical University Dresden; Dresden Germany

Funder

Helmholtz-Alberta Initiative (HAI-IDR)

Hannover biomedical research

National Institute for Allergy and Infectious Diseases

Canadian Institute for Health Research

German Research Foundation

Publisher

Wiley

Subject

Hepatology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/hep.28111/fullpdf

Reference33 articles.

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2. Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource;Smith;Hepatology,2014

3. Hepatitis C virus infection;Lauer;N Engl J Med,2001

4. New hepatitis C therapies: the toolbox, strategies, and challenges;Pawlotsky;Gastroenterology,2014

5. Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence;Mohd Hanafiah;Hepatology,2013

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