Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades-Reference-Cited by-同舟云学术

Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades

Published:2012-08-09 Issue:3 Volume:73 Page:296-305
ISSN:0270-4137
Container-title:The Prostate
language:en
Short-container-title:Prostate

Author:

Kim Seong Won,Kim Sung-Moo,Bae Hang,Nam Dongwoo,Lee Jun-Hee,Lee Seok-Geun,Shim Bum Sang,Kim Sung-Hoon,Ahn Kyoo Seok,Choi Seung-Hoon,Sethi Gautam,Ahn Kwang Seok

Funder

Korean Ministry of Education, Science and Technology

National Medical Research Council of Singapore

Publisher

Wiley

Subject

Urology,Oncology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/pros.22574/fullpdf

Reference49 articles.

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3. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database;Nikolovska-Coleska;J Med Chem,2004

4. Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products;Ahn;Mol Pharmacol,2007

5. Cell-penetrating peptide-conjugated XIAP-inhibitory cyclic hexapeptides enter into Jurkat cells and inhibit cell proliferation;Sasaki;Febs J,2008

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