Specific inhibition of FAK signaling attenuates subchondral bone deterioration and articular cartilage degeneration during osteoarthritis pathogenesis-Reference-Cited by-同舟云学术

Specific inhibition of FAK signaling attenuates subchondral bone deterioration and articular cartilage degeneration during osteoarthritis pathogenesis

Published:2020-04-23 Issue:11 Volume:235 Page:8653-8666
ISSN:0021-9541
Container-title:Journal of Cellular Physiology
language:en
Short-container-title:J Cell Physiol

Author:

Wu Hangtian¹²,Xu Ting³^ORCID,Chen Zhigang⁴,Wang Yutian¹²,Li Kaiqun¹²^ORCID,Chen Pei‐Sheng¹⁵^ORCID,Yao Zilong¹²,Su Jianwen¹²,Cheng Caiyu¹²,Wu Xiaohu¹²,Zhang Hongan¹²,Chai Yu¹⁶,Zhang Xianrong¹²,Hu Yanjun¹²,Yu Bin¹²,Cui Zhuang¹²^ORCID

Affiliation:

1. Department of Orthopaedics, Nanfang Hospital Southern Medical University Guangzhou Guangdong China

2. Department of Orthopaedics, Guangdong Provincial Key Laboratory of Bone and Cartilage Regeneration Medicine Nanfang Hospital, Southern Medical University Guangzhou Guangdong China

3. Department of Sleep Medicine Center, Nanfang Hospital Southern Medical University Guangzhou Guangdong China

4. Department of Orthopaedics and Traumatology, The Fifth Affiliated Hospital Guangzhou Medical University Guangzhou Guangdong China

5. Department of Orthopaedics Fuzhou Second Hospital Affiliated to Xiamen University Fuzhou Fujian China

6. Department of Orthopaedic Surgery, Institute for Cell Engineering Johns Hopkins University Baltimore Maryland

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcp.29709

Reference48 articles.

1. Osteoarthritis year 2010 in review: pharmacological therapies

2. Osteoarthritis induction leads to early and temporal subchondral plate porosity in the tibial plateau of mice: An in vivo microfocal computed tomography study

3. Vascular Biology and the Skeleton

4. Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation

5. Bone remodelling in osteoarthritis

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