Quantitative determination of LY‐404,039, a metabotropic glutamate 2/3 receptor agonist, in rat plasma using chemical derivatization and HPLC

Quantitative determination of LY‐404,039, a metabotropic glutamate 2/3 receptor agonist, in rat plasma using chemical derivatization and HPLC–MRM/MS

Author:

Kang Woojin¹^ORCID,Gaudette Fleur²^ORCID,Bédard Dominique¹,Beaudry Francis³⁴^ORCID,Huot Philippe¹⁵⁶

Affiliation:

1. Neurodegenerative Disease Group Montreal Neurological Institute‐Hospital (The Neuro) Montreal QC Canada

2. Plateforme de Pharmacocinétique Centre de Recherche du Centre Hospitalier de l'Université de Montréal Montreal QC Canada

3. Département de biomédecine vétérinaire Faculté de médecine vétérinaire Université de Montréal Saint‐Hyacinthe QC Canada

4. Centre de recherche sur le cerveau et l'apprentissage Université de Montréal Montreal QC Canada

5. Department of Neurology and Neurosurgery McGill University Montreal QC Canada

6. Movement Disorder Clinic, Division of Neurology, Department of Neurosciences McGill University Health Centre Montreal QC Canada

Funder

Weston Brain Institute

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

Reference19 articles.

3. Bioanalytical Method Validation Guidance for Industry. (2018 05/24/2018).

4. Preparation of ester derivatives of fatty acids for chromatographic analysis;Christie W. W.;Advances in Lipid Methodology,1993

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