Open Peer Commentary to “Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE Trials as reported by Biogen December 2019”-Reference-Cited by-同舟云学术

Open Peer Commentary to “Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE Trials as reported by Biogen December 2019”

Published:2020-11 Issue:4 Volume:17 Page:702-703
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Sabbagh Marwan Noel¹,Cummings Jeffrey¹²

Affiliation:

1. Cleveland Clinic Lou Ruvo Center for Brain Health Las Vegas Nevada USA

2. Chambers‐Grundy Center for Transformative Neuroscience Department of Brain Health School of Integrated Health Sciences University of Nevada Las Vegas USA

Funder

National Institutes of Health

National Institute of Neurological Disorders and Stroke

National Institute on Aging

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12235

Reference8 articles.

1. Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE trials as reported by Biogen, December 2019

2. Kinetic fingerprints differentiate the mechanisms of action of anti‐Aβ antibodies;Linse S;Nat Struct Mol Biol,2020

3. The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

4. Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

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