Evaluation of morphine-like effects of the mixed mu/delta agonist morphine-6-O -sulfate in rats: Drug discrimination and physical dependence

Author:

Yadlapalli Jai Shankar K.1,Bommagani Shoban Babu1,Mahelona Ryan D.2,Wan Anqi1,Gannon Brenda M.2,Penthala Narsimha R.1,Dobretsov Maxim3,Crooks Peter A.1,Fantegrossi William E.2ORCID

Affiliation:

1. Departments of Pharmaceutical Sciences; University of Arkansas for Medical Sciences; Little Rock; Arkansas 72205

2. Department of Pharmacology and Toxicology; University of Arkansas for Medical Sciences; Little Rock Arkansas 72205

3. Department of Anesthesiology; University of Arkansas for Medical Sciences; Little Rock; Arkansas 72205

Funder

National Institutes of Health

University of Arkansas for Medical Sciences

Arkansas Research Alliance

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Reference47 articles.

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2. Micro/kappa opioid interactions in rhesus monkeys: Implications for analgesia and abuse liability;Negus;Exp Clin Psychopharmacol,2008

3. Normalized demand for drugs and other reinforcers;Hursh;J Exp Anal Behav,1995

4. Abuse liability studies of opioid agonist-antagonists in humans;Preston;Drug Alcohol Depend,1991

5. Characterization of opioid agonist efficacy in a C6 glioma cell line expressing the mu opioid receptor;Emmerson;J Pharmacol Exp Ther,1996

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