Cation exchange chromatography performed in overloaded mode is effective in removing viruses during the manufacturing of monoclonal antibodies
Author:
Affiliation:
1. Biologics Technology Research LaboratoriesDaiichi Sankyo Co., Ltd. Ohra‐gun Gunma Japan
2. Graduate School of Science and TechnologyGunma University Kiryu‐shi Gunma Japan
Publisher
Wiley
Subject
Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.2858
Reference23 articles.
1. Antibodies to watch in 2017
2. Aggregates in monoclonal antibody manufacturing processes
3. Demonstration of Robust Host Cell Protein Clearance in Biopharmaceutical Downstream Processes
4. Implementation of advanced technologies in commercial monoclonal antibody production
5. Recovery and purification process development for monoclonal antibody production
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1. 1Progress, applications, challenges and prospects of protein purification technology;Frontiers in Bioengineering and Biotechnology;2022-12-06
2. Viral removal by column chromatography in downstream processing of monoclonal antibodies;Protein Expression and Purification;2022-10
3. Combinatorial peptides: A library that continuously probes low‐abundance proteins;ELECTROPHORESIS;2021-09-20
4. The prevention of an anomalous chromatographic behavior and the resulting successful removal of viruses from monoclonal antibody with an asymmetric charge distribution by using a membrane adsorber in highly efficient, anion‐exchange chromatography in flow‐through mode;Biotechnology Progress;2020-01-21
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