White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

Author:

Lee Seonjoo12,Viqar Fawad34,Zimmerman Molly E.45,Narkhede Atul3,Tosto Giuseppe36,Benzinger Tammie L.S.7,Marcus Daniel S.7,Fagan Anne M.8,Goate Alison9,Fox Nick C.10,Cairns Nigel J.11,Holtzman David M.8,Buckles Virginia8,Ghetti Bernardino12,McDade Eric8,Martins Ralph N.13,Saykin Andrew J.14,Masters Colin L.15,Ringman John M.16,Ryan Natalie S.10,Förster Stefan17,Laske Christoph18,Schofield Peter R.19,Sperling Reisa A.20,Salloway Stephen21,Correia Stephen22,Jack Clifford23,Weiner Michael24,Bateman Randall J.8,Morris John C.8,Mayeux Richard3625,Brickman Adam M.3625,

Affiliation:

1. Department of Psychiatry, College of Physicians and Surgeons; Columbia University; New York NY

2. Division of Biostatistics, New York State Psychiatric Institute; New York NY

3. Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons; Columbia University; New York NY

4. Psychology Department; Fordham University; Bronx NY

5. Department of Neurology; Albert Einstein College of Medicine; Bronx NY

6. Department of Neurology, Columbia University Medical Center and the New York Presbyterian Hospital; Columbia University; New York NY

7. Department of Radiology; Washington University School of Medicine; Saint Louis MO

8. Department of Neurology; Washington University School of Medicine; St. Louis MO

9. Department of Neuroscience; Icahn School of Medicine at Mount Sinai; New York NY

10. Dementia Research Center, Department of Neurodegenerative Disease; UCL Institute of Neurology; London United Kingdom

11. Department of Pathology and Immunology; Washington University School of Medicine; St. Louis MO

12. Department of Pathology and Laboratory Medicine; Indiana University School of Medicine; Indianapolis IN

13. Center of Excellence of Alzheimer's Disease Research and Care, School of Exercise, Biomedical and Health Sciences; Edith Cowan University; Perth Australia

14. Indiana Alzheimer Disease Center and Department of Radiology and Imaging Sciences; Indiana University School of Medicine; Indianapolis IN

15. The Florey Institute; University of Melbourne; Parkville Australia

16. Memory and Aging Center; Keck School of Medicine of University of Southern California; Los Angeles CA

17. German Center for Neurodegenerative Diseases (DZNE) München and Tübingen and Department of Nuclear Medicine; Technische Universität München (TUM); Munich Germany

18. German Center for Neurodegenerative Diseases (DZNE) and the Section for Dementia Research, Department of Cellular Neurology, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy; University of Tübingen; Tübingen Germany

19. Neuroscience Research Australia and University of New South Wales; Sydney Australia

20. Center for Alzheimer Research and Treatment; Brigham and Women's Hospital and Massachusetts General Hospital; Boston MA

21. Butler Hospital and Department of Neurology, Alpert Medical School; Brown University; Providence RI

22. Department of Psychiatry, Alpert Medical School; Brown University; Providence RI

23. Department of Radiology; Mayo Clinic; Rochester MN

24. Department of Radiology and Biomedical Imaging, Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center and Departments of Psychiatry, Radiology, Medicine, and Neurology; University of California at San Francisco; San Francisco CA

25. Gertrude H. Sergievsky Center, College of Physicians and Surgeons; Columbia University; New York NY

Funder

NIH/NIA

NIHR Queen Square Dementia BRU

German Center for Neurodegenerative Diseases (DZNE)

Brain Exit Foundation Fellowship

Publisher

Wiley

Subject

Clinical Neurology,Neurology

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