Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium-Reference-Cited by-同舟云学术

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Establishment of tissue-specific tolerance is driven by regulatory T cells selected by thymic epithelium

Published:1996-08 Issue:8 Volume:26 Page:1807-1815
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Modigliani Yves,Coutinho Antonio,Pereira Pablo,Le Douarin Nicole,Thomas-Vaslin Véronique,Burlen-Defranoux Odile,Salaün Josselyne,Bandeira Antonio

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference60 articles.

1. T cell tolerance by clonal elimination in the thymus

2. Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

3. Deletion of self-reactive T cells before entry into the thymus medulla

4. Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

5. Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

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