Human IgG isotype-specific amino acid residues affecting complement-mediated cell lysis and phagocytosis
Author:
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Reference29 articles.
1. The extended hinge region of IgG3 is not required for high phagocytic capacity mediated by Fcγ receptors, but the heavy chains must be disulfide bonded
2. The binding site for C1q on IgG
3. Influence of the hinge region on complement activation, C1q binding, and segmental flexibility in chimeric human immunoglobulins.
4. Chimeric mouse human IgG3 antibodies with an IgG4-like hinge region induce complement-mediated lysis more efficiently than IgG3 with normal hing
5. Activation of complement by an IgG molecule without a genetic hinge
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