Ocular venous occlusion in pediatrics: Should thrombophilia investigation and anticoagulant treatment be initiated?

Author:

Benish Marganit12ORCID,Shrot Shai23,Barg Assaf245,Kventsel Iris5,Elhasid Ronit12ORCID,Kenet Gili24,Levy‐Mendelovich Sarina246

Affiliation:

1. Department of Pediatric Hematology and Oncology, Dana‐Dwek Children's Hospital Tel Aviv Medical Center Tel Aviv Israel

2. Faculty of Medicine Tel Aviv University Tel Aviv Israel

3. Department of Diagnostic Imaging Sheba Medical Center Ramat Gan Israel

4. National Hemophilia and thrombosis Center, Amalia Biron thrombosis Research Institue Sheba Medical Center Ramat Gan Israel

5. Department of Pediatric Hematology‐Oncology, The Edmond and Lily Safra Children's Hospital Sheba Medical Center Ramat Gan Israel

6. Talpiot sheba leadership program Sheba medical center Ramat Gan Israel

Abstract

AbstractRetinal vein occlusion (RVO) and superior ophthalmic vein thrombosis (SOVT) are rare diseases in the pediatric population; however, the ophthalmic and neurologic morbidity are significant. As published data are scarce for these conditions, we present our experience with pediatric ocular venous thrombosis in four patients, and discuss recommended management for evaluation and treatment. We suggest performing thrombophilia workup for all pediatric patients with RVO or SOVT. In patients with thrombophilia risk factors or patients with additional thrombi, we highly recommend initiating anticoagulation therapy. There is a need for more research in order to determine the optimal management strategy.

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

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