Affiliation:
1. Department of Chemistry and Chemical Biology McMaster University 1280 Main Street West Hamilton Ontario L8S 4M1 Canada
2. Centre for Advanced Light Microscopy McMaster University 1280 Main Street West Hamilton Ontario L8S 4M1 Canada
3. Brockhouse Institute for Materials Research McMaster University 1280 Main Street West Hamilton Ontario L8S 4M1 Canada
Abstract
AbstractA key challenge for sensor miniaturization is to create electrodes with smaller footprints, while maintaining or increasing sensitivity. In this work, the electroactive surface of gold electrodes was enhanced 30‐fold by wrinkling followed by chronoamperometric (CA) pulsing. Electron microscopy showed increased surface roughness in response to an increased number of CA pulses. The nanoroughened electrodes also showed excellent fouling resistance when submerged in solutions containing bovine serum albumin. The nanoroughened electrodes were used for electrochemical detection of Cu2+ in tap water and of glucose in human blood plasma. In the latter case, the nanoroughened electrodes allowed highly sensitive enzyme‐free sensing of glucose, with responses comparable to those of two commercial enzyme‐based sensors. We anticipate that this methodology to fabricate nanostructured electrodes can accelerate the development of simple, cost‐effective, and high sensitivity electrochemical platforms.
Funder
Natural Sciences and Engineering Research Council of Canada
Ontario Ministry of Research and Innovation
Canada Research Chairs
Government of Ontario
Subject
General Chemistry,Catalysis
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献