S ‐Adenosyl‐ l ‐ethionine is a Catalytically Competent Analog of S ‐Adenosyl‐ l ‐methionine (SAM) in the Radical SAM Enzyme HydG-Reference-Cited by-同舟云学术

S ‐Adenosyl‐ l ‐ethionine is a Catalytically Competent Analog of S ‐Adenosyl‐ l ‐methionine (SAM) in the Radical SAM Enzyme HydG

Published:2021-01-18 Issue:9 Volume:60 Page:4666-4672
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Impano Stella¹^ORCID,Yang Hao²^ORCID,Shepard Eric M.¹^ORCID,Swimley Ryan¹^ORCID,Pagnier Adrien¹^ORCID,Broderick William E.¹^ORCID,Hoffman Brian M.²^ORCID,Broderick Joan B.¹^ORCID

Affiliation:

1. Department of Chemistry & Biochemistry Montana State University Bozeman MT 59717 USA

2. Department of Chemistry Northwestern University Evanston IL 60208 USA

Funder

Basic Energy Sciences

National Institute of General Medical Sciences

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202014337

Reference47 articles.

1. Radical SAM catalysis via an organometallic intermediate with an Fe–[5′-C]-deoxyadenosyl bond

2. Paradigm Shift for Radical S-Adenosyl-l-methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis

3. Radical S-Adenosylmethionine Enzymes

4. Mechanism of Radical Initiation in the Radical S-Adenosyl-l-methionine Superfamily

5. Radical Mechanisms of Enzymatic Catalysis

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