Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase**-Reference-Cited by-同舟云学术

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Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase**

Published:2022-10-21 Issue:47 Volume:61 Page:
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew Chem Int Ed

Author:

Bolding Julie E.¹,Martín‐Gago Pablo¹,Rajabi Nima¹,Gamon Luke F.²,Hansen Tobias N.¹^ORCID,Bartling Christian R. O.¹,Strømgaard Kristian¹,Davies Michael J.²^ORCID,Olsen Christian A.¹^ORCID

Affiliation:

1. Center for Biopharmaceuticals & Department of Drug Design and Pharmacology Faculty of Health and Medical Sciences University of Copenhagen Universitetsparken 2 DK-2100 Copenhagen Denmark

2. Department of Biomedical Sciences Faculty of Health and Medical Sciences University of Copenhagen Blegdamsvej 3 DK-2200 Copenhagen Denmark

Funder

Carlsbergfondet

Novo Nordisk Fonden

Lundbeckfonden

Danmarks Frie Forskningsfond

H2020 European Research Council

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202204565

Reference77 articles.

1.

2. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

3. The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

4. The Substrate Specificity of Sirtuins

5.

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4. Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update;Journal of Medicinal Chemistry;2024-05-07

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