Development of Generic G Protein Peptidomimetics Able to Stabilize Active State G s Protein‐Coupled Receptors for Application in Drug Discovery-Reference-Cited by-同舟云学术

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Development of Generic G Protein Peptidomimetics Able to Stabilize Active State G s Protein‐Coupled Receptors for Application in Drug Discovery

Published:2021-03-23 Issue:18 Volume:60 Page:10247-10254
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Mannes Morgane¹,Martin Charlotte¹,Triest Sarah²,Pia Dimmito Marilisa¹³,Mollica Adriano³,Laeremans Toon²,Menet Christel J.²,Ballet Steven¹^ORCID

Affiliation:

1. Research Group of Organic Chemistry Vrije Universiteit Brussel Pleinlaan 2 1050 Brussels Belgium

2. Confo Therapeutics N.V. Technologiepark-Zwijnaarde 94 9052 Ghent Belgium

3. Department of Pharmacy University “G. d'Annunzio” of Chieti-Pescara Via dei Vestini 31 66100 Chieti Italy

Funder

Innoviris

Vrije Universiteit Brussel

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202100180

Reference47 articles.

1. The structure and function of G-protein-coupled receptors

2. Methodological advances: the unsung heroes of the GPCR structural revolution

3. Impact of GPCR Structures on Drug Discovery

4. The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery

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1. A rapid, tag-free way to purify functional GPCRs;Journal of Biological Chemistry;2024-01

2. Structure-Based Design and Synthesis of Stapled ¹⁰Panx1 Analogues for Use in Cardiovascular Inflammatory Diseases;Journal of Medicinal Chemistry;2023-09-13

3. Accessible and Generalizable in Vitro Luminescence Assay for Detecting GPCR Activation;ACS Measurement Science Au;2023-07-07

4. An accessible and generalizable in vitro luminescence assay for detecting GPCR activation;2023-03-02

5. New Insights into the Structure and Function of Class B1 GPCRs;Endocrine Reviews;2022-12-22

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