Exploring Unconventional SAM Analogues To Build Cell‐Potent Bisubstrate Inhibitors for Nicotinamide <i>N</i> ‐Methyltransferase-Reference-Cited by-同舟云学术

Exploring Unconventional SAM Analogues To Build Cell‐Potent Bisubstrate Inhibitors for Nicotinamide N ‐Methyltransferase

Published:2022-02-23 Issue:16 Volume:61 Page:
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew Chem Int Ed

Author:

Iyamu Iredia D.¹,Vilseck Jonah Z.²,Yadav Ravi³,Noinaj Nicholas³,Huang Rong¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology Purdue Institute for Drug Discovery Purdue University Center for Cancer Research Purdue University West Lafayette IN 47907 USA

2. Department of Biochemistry and Molecular Biology Center for Computational Biology and Bioinformatics Indiana University School of Medicine Indianapolis IN 46202 USA

3. Department of Biological Sciences, Markey Center for Structural Biology and the Purdue Institute of Inflammation Immunology and Infectious Disease Purdue University West Lafayette IN 47907 USA

Funder

Ralph W. and Grace M. Showalter Research Trust Fund

National Institutes of Health

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202114813

Reference38 articles.

1. DNA Methylation and Cancer

2. DNA Methyltransferases, DNA Damage Repair, and Cancer