Affiliation:
1. Department of Chemistry Pennsylvania State University University Park PA 16802 USA
Abstract
AbstractWe disclose a Ni‐catalyzed regioselective dialkylation reaction of alkenylarenes with α‐halocarbonyls and alkylzinc reagents. The reaction produces γ‐arylated alkanecarbonyl compounds with the generation of two new C(sp3)−C(sp3) bonds at the vicinal carbons of alkenes. This reaction is effective for the use of primary, secondary and tertiary α‐halocarboxylic esters, amides and ketones in conjunction with primary and secondary alkylzinc reagents as the sources of two C(sp3) carbons for the dialkylation of terminal and cyclic internal alkenes.
Funder
National Institute of General Medical Sciences
Subject
General Chemistry,Catalysis
Cited by
8 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献