A Light‐Powered Single‐Stranded DNA Molecular Motor with Colour‐Selective Single‐Step Control

Author:

Anderson Tommy1,Wu Wei1,Sirbu Olga1,Tong Keshao1,Siti Winna1,Rui Liu Xiao1,Kou Bo2,Murayama Keiji3,Asanuma Hiroyuki3,Wang Zhisong14ORCID

Affiliation:

1. Department of Physics National University of Singapore 117542 Singapore Singapore

2. Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology School of Materials Science and Engineering Nanjing Institute of Technology 211100 Nanjing China

3. Department of Biomolecular Engineering Graduate School of Engineering Nagoya University 464-8603 Nagoya Japan

4. Integrated Science and Engineering Programme NUS Graduate School 119077 Singapore Singapore

Abstract

AbstractTop‐down control of small motion is possible through top‐down controlled molecular motors in replacement of larger actuators like MEMS or NEMS (micro‐ or nano‐electromechanical systems) in the current precision technology. Improving top‐down control of molecular motors to every single step is desirable for this purpose, and also for synchronization of motor actions for amplified effects. Here we report a designed single‐stranded DNA molecular motor powered by alternated ultraviolet and visible light for processive track‐walking, with the two light colours each locking the motor in a full directional step to allow saturated driving but no overstepping. This novel nano‐optomechanical driving mechanism pushes the top‐down control of molecular motors down to every single step, thus providing a key technical capability to advance the molecular motor‐based precision technology and also motor synchronization for amplified effects.

Publisher

Wiley

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