Mutant‐Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug‐Resistant Mutations-Reference-Cited by-同舟云学术

Mutant‐Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug‐Resistant Mutations

Published:2020-07-09 Issue:34 Volume:59 Page:14481-14489
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Jang Jaebong¹²,To Ciric³,De Clercq Dries J. H.¹,Park Eunyoung¹,Ponthier Charles M.¹,Shin Bo Hee³,Mushajiang Mierzhati³,Nowak Radosław P.¹,Fischer Eric S.¹,Eck Michael J.¹,Jänne Pasi A.³⁴,Gray Nathanael S.¹^ORCID

Affiliation:

1. Department of Cancer Biology Dana-Farber Cancer Institute Department of Biological Chemistry and Molecular Pharmacology Harvard Medical School Longwood Center 360 Longwood Avenue Boston MA 02215 USA

2. Current address: College of Pharmacy Korea University 2511 Sejong-ro Sejong 30019 Republic of Korea

3. Lowe Center for Thoracic Oncology Dana-Farber Cancer Institute Department of Medical Oncology Dana-Farber Cancer Institute Department of Medicine Harvard Medical School Longwood Center 360 Longwood Avenue Boston MA 02215 USA

4. Belfer Center for Applied Cancer Science Longwood Center 360 Longwood Avenue Boston MA 02215 USA

Funder

National Institutes of Health

National Cancer Institute

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202003500

Reference54 articles.

2. Frequency of and variables associated with the EGFR mutation and its subtypes