Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics
Author:
Affiliation:
1. Department of Chemistry University of Cambridge Lensfield Road Cambridge CB2 1EW UK
2. Cancer Research (UK) Cambridge Institute University of Cambridge Robinson Way Cambridge CB2 0RE UK
Funder
Engineering and Physical Sciences Research Council
Royal Society
Publisher
Wiley
Subject
General Chemistry,Catalysis
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202010090
Reference53 articles.
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2. Cytotoxic peptides from the marine sponge Cymbastela sp.
3. Hemiasterlin Methyl Ester
4. Cytotoxic and tubulin-interactive hemiasterlins from Auletta sp. and Siphonochalina spp. sponges
5. Milnamide A, an unusual cytotoxic tripeptide from the marine sponge Auletta cf. constricta
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