Regio‐ and Stereoselective Hydroelementation of SF<sub>5</sub>‐Alkynes and Further Functionalizations.-Reference-Cited by-同舟云学术

Regio‐ and Stereoselective Hydroelementation of SF₅‐Alkynes and Further Functionalizations.

Published:2023-03-30 Issue:19 Volume:62 Page:
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew Chem Int Ed

Author:

Popek Lucas¹^ORCID,Cabrera‐Trujillo Jorge Juan²^ORCID,Debrauwer Vincent¹^ORCID,Blanchard Nicolas¹^ORCID,Miqueu Karinne²^ORCID,Bizet Vincent¹^ORCID

Affiliation:

1. Université de Haute-Alsace Université de Strasbourg, CNRS, LIMA, UMR 7042 68000 Mulhouse France

2. CNRS/Université de Pau et des Pays de l'Adour, E2S-UPPA, IPREM UMR 5254 64053 Pau cedex 09 France

Abstract

AbstractHerein is described a fully regio‐ and stereoselective hydroelementation reaction of SF5‐alkynes with N, O and S‐nucleophiles and further functionalization of the corresponding Z‐(hetero)vinyl‐SF5 intermediates, a suitable platform to access α‐SF5 ketones and esters, β‐SF5 amines and alcohols under mild reaction conditions. Experimental and computational comparative studies between SF5‐ and CF3‐alkynes have been performed to highlight and explain the difference of reactivity and selectivity observed between these two fluorinated motifs.

Funder

Agence Nationale de la Recherche

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202300685

Reference120 articles.

1. https://www.nobelprize.org/prizes/chemistry/2021/summary/.

2. For reviews about enamine see:

3. Asymmetric Enamine Catalysis