Enantioconvergent Reductive C(sp)−C(sp<sup>3</sup>) Cross‐Coupling to Access Chiral α‐Alkynyl Phosphonates Under Dual Nickel/Photoredox Catalysis-Reference-Cited by-同舟云学术

Enantioconvergent Reductive C(sp)−C(sp³) Cross‐Coupling to Access Chiral α‐Alkynyl Phosphonates Under Dual Nickel/Photoredox Catalysis

Published:2023-03-28 Issue:18 Volume:62 Page:
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew Chem Int Ed

Author:

Wang Hepan¹,Wu Xiaoqiang¹,XU Tao¹^ORCID

Affiliation:

1. Shanghai Key Laboratory of Chemical Assessment and Sustainability School of Chemical Science and Engineering Tongji University 1239 Siping Road Shanghai 200092 P. R. China

Abstract

AbstractTransition‐metal‐catalyzed asymmetric carbon−carbon bond formation to forge phosphonates with an α‐chiral carbon center through C(sp3)−C(sp3) and C(sp2)−C(sp3) couplings has been successful. However, the enantioselective C(sp)−C(sp3) coupling has not yet been disclosed. Reported herein is an unprecedented enantioconvergent cross‐coupling of alkynyl bromides and α‐bromo phosphonates to deliver chiral α‐alkynyl phosphonates.

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202218299

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