Chemoenzymatic Synthesis of 9NHAc‐GD2 Antigen to Overcome the Hydrolytic Instability of O ‐Acetylated‐GD2 for Anticancer Conjugate Vaccine Development

Author:

Wu Xuanjun123ORCID,Ye Jinfeng1,DeLaitsch Andrew T.4,Rashidijahanabad Zahra23,Lang Shuyao23,Kakeshpour Tayeb2,Zhao Yuetao235,Ramadan Sherif236ORCID,Saavedra Paulo Vilar7,Yuzbasiyan‐Gurkan Vilma8,Kavunja Herbert29,Cao Hongzhi1,Gildersleeve Jeffrey C.4,Huang Xuefei2310ORCID

Affiliation:

1. National Glycoengineering Research Center Shandong Key Laboratory of Carbohydrate Chemistry and Glycobiology Shandong University Qingdao Shandong 266237 China

2. Department of Chemistry Michigan State University East Lansing MI 48824 USA

3. Institute for Quantitative Health Science and Engineering Michigan State University East Lansing MI 48824 USA

4. Chemical Biology Laboratory Center for Cancer Research National Cancer Institute National Institutes of Health Frederick MD USA

5. School of Life Sciences Central South University Changsha Hunan 410013 China

6. Chemistry Department Faculty of Science Benha University Benha Qaliobiya 13518 Egypt

7. Department of Small Animal Clinical Sciences Michigan State University East Lansing MI 48824 USA

8. Department of Microbiology and Molecular Genetics Michigan State University East Lansing MI 48824 USA

9. Iaso Therapeutics 4942 Dawn Avenue East Lansing MI 48823 USA

10. Department of Biomedical Engineering Michigan State University East Lansing MI 48824 USA

Funder

National Cancer Institute

National Science Foundation of Sri Lanka

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Chemistry,Catalysis

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