OSI‐027 inhibits the tumorigenesis of colon cancer through mediation of c‐Myc/FOXO3a/PUMA axis
Author:
Affiliation:
1. Department of Gastroenterology Shanghai Tenth People's Hospital, School of Medicine Tongji University Shanghai China
2. Department of Gastroenterology HwaMei Hospital University of Chinese Academy of Sciences Ningbo Zhejiang China
Publisher
Wiley
Subject
Cell Biology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbin.11792
Reference35 articles.
1. Myc and PI3K/AKT signaling cooperatively repress FOXO3a-dependent PUMA and GADD45a gene expression
2. Colon Cancer, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology
3. Preclinical Characterization of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2: Distinct from Rapamycin
4. The novel anti-MEK small molecule AZD6244 induces BIM-dependent and AKT-independent apoptosis in diffuse large B-cell lymphoma
5. Gossypol decreased cell viability and down-regulated the expression of a number of genes in human colon cancer cells
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. mTORC2: A neglected player in aging regulation;Journal of Cellular Physiology;2024-07-10
2. Study on the effects of rapamycin and the mTORC1/2 dual inhibitor OSI-027 on the metabolism of colon cancer cells based on UPLC-MS/MS metabolomics;Investigational New Drugs;2024-06-25
3. Clinical value of molecular subtypes identification based on anoikis-related lncRNAs in castration-resistant prostate cancer;Cellular Signalling;2024-05
4. Roles of Rictor alterations in gastrointestinal tumors (Review);Oncology Reports;2024-01-04
5. Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease;Signal Transduction and Targeted Therapy;2023-10-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3